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  • Synovial fluid protein levels may predict osteochondral allograft transplantation outcomes

    Elevated levels of synovial fluid proteins may be associated with poor outcomes after osteochondral allograft transplantation. Synovial fluid protein levels may be used as a biomarker to predict outcomes.

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  • Corticosteroids Versus Platelet-Rich Plasma Injections for Knee Osteoarthritis: Where is there More Evidence? A Systematic Review of 60 Years of Literature

    PRP injections for knee OA have been documented in more studies and in larger patient numbers compared with CS injections. The higher number of high-level trials for PRP, combined with the lower safety and efficacy documented for CS by previous meta-analyses directly comparing the two products, strongly suggests reconsidering current guidelines that favor CS, highlighting PRP’s body of evidence and the potential role in the effective and safe treatment of knee OA.

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  • Stem Cell Therapies for Spinal Cord Injury in Humans: A Review of Recent Clinical Research

    Recently, cell transplantation has emerged as a promising treatment for spinal cord injury (SCI). Over the past decade, numerous clinical studies of SCI have been conducted using various types of cells, including fetal neural stem/progenitor cells (NS/PCs), pluripotent stem cell-derived NS/PCs, mesenchymal stem/stromal cells (MSCs), olfactory ensheathing cells, and Schwann cells. Promising results have been reported for patients with subacute SCI, especially in studies involving MSCs, such as those conducted with Stemirac, although no universally recognized breakthroughs have been achieved. Allogenic NS/PCs may offer advantages over autologous MSCs because they have the potential for cell engraftment within the spinal cord and can be prepared in advance, facilitating their administration during the hyperacute phase.

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  • Hallux Rigidus with an Increased or Equal First Metatarsal Length after a Cheilectomy and First Metatarsal Shortening Osteotomy (FMSO) Using a Small Shortening Scarf: A Retrospective 7-year Clinical and Gait Analysis Follow-up

    To evaluate the long-term outcomes of a combined surgical approach using cheilectomy and shortening SCARF osteotomy for moderate hallux rigidus (Coughlin grades 2-3) in active patients with a first metatarsal index equal to or longer than the second metatarsal.

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  • What Can Happen to Your Feet When You Wear Sandals Every Day

    Sandals may feel great in the summer, but wearing them too often can lead to stubbed toes, blisters, or joint pain. Many sandals lack proper arch support and cushioning, increasing the risk of foot and leg issues.

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